Pioneering advances at the forefront of pharma

Featured, Pharmaceuticals, Technology 2021-01-07

Pioneering research holds the potential to transform the pharmaceutical sector, and breakthroughs continue to be made across the industry. From facilitating safer collaborations throughout the COVID-19 pandemic to increasing sustainability and efficiency, read on to discover exciting advances that promise to change the face of the industry. You can also explore these in more detail in our 9th Chemistry World issue – At the Forefront of Pharma!

Ensuring safer medicines 

A product recall due to issues regarding safety or efficacy is disastrous, both for patients and for the pharmaceutical company producing the drug. That’s why an integral part of the drug development process is the identification of pharmaceutical impurities formed alongside the desired drug product, and the assessment of their impact on the safety and efficacy of the drug.

Toronto Research Chemicals (TRC), a specialty chemicals company, leverages state-of-the-art technologies such as mass spectrometry and NMR-based approaches to rapidly identify pharmaceutical impurities. The company also develops reliable impurity synthesis routes to allow impurities to be studied further and for their impact on drug efficacy and safety to be determined. This valuable service ensures that drugs reaching the market do exactly what they say on the box, with no unpleasant surprises.

Learn more about the importance of preventing pharmaceutical impurities from reaching the market here.

Creating sustainable approaches

Many industries are currently seeking out routes to both financial and environmental sustainability, and Pharma is no exception. Innovative chemical pathways and next-generation, sustainable technologies are key in order to meet the standards of Industry 4.0 and develop environmentally friendly, efficient and reliable routes to target compounds.

Umicore Precious Metals Chemistry, a materials technology and recycling company, is developing advanced techniques to promote closed-loop catalyst life cycles. By incorporating this method early in pharmaceutical development, users can simplify their operations and create more sustainable routes to industrially important molecules. Simultaneously, drug developers can free up time to focus on the myriad of other challenges associated with bringing a drug to market. Consequently, by leveraging the power of new catalytic approaches, it is anticipated that a range of new possibilities will be opened up for increasing sustainability in the pharmaceutical sector.

Learn more about innovations in catalysis here.

Improving efficiency with innovative technologies

Across many industries, the adoption of advanced manufacturing techniques such as AI and digital simulations has facilitated dramatic improvements. Though the need for standardisation and regulatory approval can make new technologies difficult to implement in Pharma, using current methods medicines can take significant amounts of time and resources to develop and produce.

That’s why, as part of two contracts from the FDA, the Austria-based Research Center for Pharmaceutical Engineering (RCPE) is planning to develop next-generation techniques to revolutionise Pharma. The projects centre on concepts such as AI-enhanced quality control and in silico modelling for product and process development. By improving efficiency in drug development and manufacture, these technologies promise to minimise waste, prevent excess resource usage, and, crucially, reduce manufacturing times. This may allow life-saving medicines to be delivered at an accelerated pace in the future, ultimately benefiting patients worldwide.

Learn more about the innovative pharmaceutical technologies being developed by the RCPE here.

Collaboration gone virtual

Innovation is at the heart of the pharmaceutical industry, particularly when it comes to the development of new therapeutics. However, with ongoing industry-wide challenges like COVID-19 and Brexit, the journey from innovative idea to life-changing treatment is more complex than ever. In order to allow new treatments to continue reaching the patients who need them, industry leaders and academics from across the sector must have the opportunity to exchange insights into current challenges and develop solutions.

Providing a platform to facilitate these valuable conversations was the primary goal of Life Science Integrates’ Pharma Integrates event. The unique one-day event brought together professionals from across the industry to discuss and debate the future of healthcare across three areas – Treatments, Trends and Technology. The event further provided a comprehensive look into drug discovery and development and facilitated collaborations that will lead to improved outcomes for patients around the world.

Learn more about the collaborations fostered by Pharma Integrates 2020 here.

Would you like to learn more about these topics? Be sure to check out our latest supplement in collaboration with Chemistry World! In our 9th issue, we cover a range of exciting advances at the forefront of Pharma. #ForefrontPharma